Cancer focal hepatic lesions, Duplicate citations
The hepatic affection induced by chemotherapy appears in children in cases of prolonged therapy, chronic diseases, or other associated conditions.
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Hepatotoxicity clinically develops through hepatic disorder, cholestatic or mixed hepato-cholestatic manifestations and systematic affection.
There are no specific hystological or biochemical characteristics for diagnostic of hepatotoxicity.
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- Distant metastases through blood with prevalent liver location are detected late in disease progression, in an advanced stage, when therapeutic possibilities are often limited to palliative therapy.
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- Viorel Scripcariu - Citations Google Scholar Colorectal cancer during pregnancy Colorectal cancer hepatic metastasis Citations en double Abstract Aim: Malignant tumors localized in the digestive tract have a tendency to local growth and invasion with lymph node metastasis.
- Unfortunately, it does not have specific signs and symptoms, being associated with an aggressive evolution and a poor prognosis if left untreated.
The international criteria for asessing the hepatotoxicity includes the bilirubin, the transaminasis, GGT, FA, albumin and the flow on the vein. It has been noticed that these neuroendocrine cancer death rate are not enough for the right assesssment of the chemotherapics hepatotoxicity. Thus it is required the abdominal ultrasonography and computerised tomography for the identification of billiary tract, vascularisation, associated conditions and the degree of fibrosis; also, the hepatic biopsy may be necessary.
Aggressive variants of prostate cancer - Are we ready to apply specific treatment right now? Cancer Treat Rev. In most cases, prostate cancer essentially depends on androgen receptor signaling axis, even in castration-resistant setting, and hence may be targeted by second generation hormonal therapy. However, a subset of patients bears androgen-independent cancer biology with a short-term response to hormonal treatment, early and extensive visceral metastases, low PSA levels and poor outcomes. Identification and specific management of these rapidly fatal malignancies is of an unmet medical need since their classification and utilized therapeutic regimens vary significantly.
Acustic radiation force imaging ARFI is an elastographic method which allows valid, accurate and flexible evaluation of liver stiffness, a quantification with a strong correlation with the fibrosis stage, not influenced by steatosis. In conclusion, the hepatic toxicity showed by alterated hepatic biochemical tests and by symptomes of hepatopathy needs a proper appreciation of the hepatic modifications, which cancer focal hepatic lesions be obtained through hepatic biopsy or by assessing the hepatic elasticity through elastography.
Thus, real-time elastography is an useful tool in assessing the chemotherapics hepatotoxicity in children with cancer.
The effect of chemotherapy on liver function in children with cancer. Morphologic spectrums of drug-induced liver disease. Gastroenterol Clin N Am ; Hepatotoxicity of chemotherapy. Oncologist ; 6: Tissieare P, DeVictor Djr.
Fulminant hepatic falure in transplantation. Rogers Textbook of Paediatric Intensive Care. General principles of chemotherapy. Principles cancer focal hepatic lesions Practice of Pediatric Oncology.
Benichou C. Criteria of drug-induced liver disorders: report of an international consensus meeting. J Hepatol ; Development and validation of a clinical scale for the diagnosis of drug-induced hepatitis.
Colorectal cancer hepatic metastasis
Hepatol ; Drug elimination in chronic liver diseases. J Hepatol ; S2: Cyclophosphamide induced hepatotoxicity in a patient with Wegeners granulomatosis. Mayo Clin Proc ; Roberts EA.
Drug-induced liver disease. Liver Disease In Children. DeSmet VJ. Drug induced liver disease: pathogenetic mechanisms and histopathological lesions.
Eur J Med ; 2: Aubrey DA. Massive hepatic necrosis after cyclophosphamide. Br Med J cancer focal hepatic lesions 3: Reversible hpv genital itching steatosis in patients treated with interferon alfa-2a and 5-fluorouracil.
Cancer ; Ultrasonic elastography in clinical quantitative assessment of fatty liver. World J Gastroenterol ; 16 37 : L-Asparaginase: therapeutic and toxic effects in patients with neoplastic disease. N Engl J Med ; Kearney S.
Pediatr Blood Cancer Toxicity of L-asparaginase in children with advanced leukemia. Land Cancer ; 30 2 : Hepatic toxicity associated with fluorouracil plus levamisole adjuvant cancer focal hepatic lesions. J Clin Oncol ; Medical Ultrasonography ; 12 1 : Elastography: ultrasonic estimation and imaging of the elastic properties of tissues. J Eng Med ; Advances in ultrasound.
Eur Radiol ; 7 Sarvazyan A. Diversity of biomedical applications of acoustic radiation force. Ultrasonics ; 50 2 : Biomedical applications of radiation force of ultrasound: historical roots and physical basis. Ultrasound Med Biol ; 36 9 : ARFI imaging for noninvasive material characterization of atherosclerosis.
Part II: toward in vivo characterization. Ultrasound Med Biol ; Liver ablation guidance with acoustic radiation force impulse imaging: challengesand opportunities. Phys Med Biol ; In vivo visualization of abdominal malignancies with acoustic radiation force elastography.
Acoustic radiation force impulse imaging of the abdomen: demonstration of feasibility and utility. Frame rate considerations forreal-time abdominal acoustic radiation force impulse imaging. Ultrason Imaging ; Quantifying hepatic shear modulus in vivo using acoustic radiationforce.
Shear properties of mammalian tissues at low megahertz frequencies.
J Acoust Soc Am ; Ultrasonic shear wave properties of soft tissues and tissuelike materials. Lazebnik R. Robust principal component analysis and clustering methods forautomated classifcation of tissue response to ARFI excitation. Acoustic radiationforce impulse imaging: in vivo demonstration of clinical feasibility. An integrated indenter- -ARFI imaging system for tissue stiffness quantifcation. Acoustic radiation force elastography versus transient elastography for non-invasive assessment of liver fbrosis in viral hepatitis: a new alternative?
Hepatol ; A. Quantifcation of hepatic fbrosis with a new US technique virtualtouch analysis : correlation with pathologic fndings. Eur Radiol ; S Lees WR.
Acoustic radiation force imaging: a new method forquantifying hepatic fbrosis. Eur Radiol ; S Acoustic radiation force imaging ARFI as a new method of ultrasonographic elastography allows accurate and fexible assessment of liver stiffness.
J Hepatol ; S Medical Ultrasonography ; 12 Suppl. Performance of a new elastographic method ARFI technology compared to unidimensional transient elastography in the noninvasive assessment of chronic hepatitis C.
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Preliminary results. J Gastrointestin Liver Dis ; 18 3 : Liver fbrosis in viral hepatitis: noninvasive assessment with acoustic radiation force impulse imaging versus transient elastography. Radiol ; Acoustic radiation force impulse elastography for the evaluation of focal solid hepatic lesions.
Ultrasound Med Biol ; 36 2 : Acoustic radiation force imaging sonoelastography for noninvasive staging of liver fbrosis. World J Gastroenterol ; 28 cancer focal hepatic lesions 44 : Acoustic radiation force impulse elastography for chronic liver disease: comparison with ultrasound-based scores of experienced radiologists, Child-Pugh scores and liver function tests. Ultrasound Med Biol ; 36 10 :